More than 15.000 molecules were scanned in the laboratories of Bahçeşehir University (BAU) with a special algorithm developed for virtual scanning and molecular modeling studies, and biological tests were applied to the selected 25 molecules.
It was determined that the molecule named Montelukast was effective on SARS-CoV-2. It has been shown that Montelukast prevents the virus from entering and reproducing in the cell.
“The most important feature of this drug is that the virus both prevents the Spike / ACE2 interaction before entering the cell and has a molecular mechanism to prevent the proliferation of the main protease enzyme in the cell.
In the analyzes performed in virus neutralization tests, it was found that drug treatment before the virus infection also delayed the effect of the virus” he said; the director of the project.
